University of California, Berkeley
Department of Integrative Biology
Office: 4095 Valley Life Sciences Building
slbernstein[at] berkeley [dot] edu
Department of Integrative Biology
Office: 4095 Valley Life Sciences Building
slbernstein[at] berkeley [dot] edu
Appointments and Education
BA, Biochemistry and Cell Biology
Minor, Art History
University of California, San Diego
Minor, Art History
University of California, San Diego
Research Interests
Publications
Karageorgi, M., S.C. Groen, K.I. Verster, J.M. Aguilar, F. Sumbul, A.P. Hastings, J.N. Pelaez, S.L. Bernstein, T. Matsunaga, M. Astourian, G. Guerra, F. Rico, S. Dobler, A.A. Agrawal & N.K. Whiteman (2019). Genome editing retraces the evolution of toxin resistance in the monarch butterfly. Nature 574: 409-412
Cai F, Bernstein SL, Wilson SC, Kerfeld CA. Production and Characterization of
Synthetic Carboxysome Shells with Incorporated Luminal Proteins. Plant Physiology January 20, 2016 pp.01822.2015. http://dx.doi.org/10.1104/pp.15.01822
Cai F, Sutter M, Bernstein SL, Kinney JN, Kerfeld CA. Engineering Bacterial Microcompartment Shells: Chimeric Shell Proteins and Chimeric Carboxysome Shells. ACS Synth Biol. 2014 Aug 12. http://pubs.acs.org/doi/abs/10.1021/sb500226j
Lassila JK, Bernstein SL, Kinney JN, Axen SD, Kerfeld CA. Assembly of Robust Bacterial Microcompartment Shells Using Building Blocks from an Organelle of Unknown Function. J Mol Biol. 2014 May 29; 426(11):2217-2228 doi:10.1016/j.jmb.2014.02.025
Cameron JC, Wilson SC, Bernstein SL, Kerfeld CA. Biogenesis of a Bacterial Organelle: The Carboxysome Assembly Pathway. Cell. 2013 Nov 21;155:1131-1140.
Bourne Y, Watson MH, Arvai AS, Bernstein SL, Reed SI, Tainer JA. Crystal structure and mutational analysis of the Saccharomyces cerevisiae cell cycle regulatory protein Cks1: implications for domain swapping, anion binding and protein interactions. Structure. 2000 Aug 15;8(8):841-50
Watson MH, Bourne Y, Arvai AS, Hickey MJ, Santiago A, Bernstein SL, Tainer JA, Reed SI. A mutation in the human cyclin-dependent kinase interacting protein, CksHs2, interferes with cyclin-dependent kinase binding and biological function, but preserves protein structure and assembly. J Mol Biol. 1996 Sep 6;261(5):646-57.
Forest KT, Bernstein SL, Getzoff ED, So M, Tribbick G, Geysen HM, Deal CD, Tainer JA. Assembly and antigenicity of the Neisseria gonorrhoeae pilus mapped with antibodies. Infect Immun. 1996 Feb;64(2):644-52.
Bourne Y, Arvai AS, Bernstein SL, Watson MH, Reed SI, Endicott JE, Noble ME, Johnson LN, Tainer JA. Crystal structure of the cell cycle-regulatory protein suc1 reveals a beta-hinge conformational switch. Proc Natl Acad Sci U S A. 1995 Oct 24;92(22):10232-6.
McTigue MA, Bernstein SL, Williams DR, Tainer JA. Purification and crystallization of a schistosomal glutathione S-transferase. Proteins. 1995 May;22(1):55-7.
Parge HE, Bernstein SL, Deal CD, McRee DE, Christensen D, Capozza MA, Kays BW, Fieser TM, Draper D, So M, Getzoff ED, Tainer JA. Biochemical purification and crystallization of the fiber-forming protein pilin from Neisseria gonorrhoeae. JBC. 1990 Feb 4;265(4)2278-2285.
Parge HE, McRee DE, Capozza MA, Bernstein SL, Getzoff ED, Tainer JA.
Three dimensional structure of bacterial pili. Antonie Van Leeuwenhoek. 1987;53(6):447-53.
Cai F, Bernstein SL, Wilson SC, Kerfeld CA. Production and Characterization of
Synthetic Carboxysome Shells with Incorporated Luminal Proteins. Plant Physiology January 20, 2016 pp.01822.2015. http://dx.doi.org/10.1104/pp.15.01822
Cai F, Sutter M, Bernstein SL, Kinney JN, Kerfeld CA. Engineering Bacterial Microcompartment Shells: Chimeric Shell Proteins and Chimeric Carboxysome Shells. ACS Synth Biol. 2014 Aug 12. http://pubs.acs.org/doi/abs/10.1021/sb500226j
Lassila JK, Bernstein SL, Kinney JN, Axen SD, Kerfeld CA. Assembly of Robust Bacterial Microcompartment Shells Using Building Blocks from an Organelle of Unknown Function. J Mol Biol. 2014 May 29; 426(11):2217-2228 doi:10.1016/j.jmb.2014.02.025
Cameron JC, Wilson SC, Bernstein SL, Kerfeld CA. Biogenesis of a Bacterial Organelle: The Carboxysome Assembly Pathway. Cell. 2013 Nov 21;155:1131-1140.
Bourne Y, Watson MH, Arvai AS, Bernstein SL, Reed SI, Tainer JA. Crystal structure and mutational analysis of the Saccharomyces cerevisiae cell cycle regulatory protein Cks1: implications for domain swapping, anion binding and protein interactions. Structure. 2000 Aug 15;8(8):841-50
Watson MH, Bourne Y, Arvai AS, Hickey MJ, Santiago A, Bernstein SL, Tainer JA, Reed SI. A mutation in the human cyclin-dependent kinase interacting protein, CksHs2, interferes with cyclin-dependent kinase binding and biological function, but preserves protein structure and assembly. J Mol Biol. 1996 Sep 6;261(5):646-57.
Forest KT, Bernstein SL, Getzoff ED, So M, Tribbick G, Geysen HM, Deal CD, Tainer JA. Assembly and antigenicity of the Neisseria gonorrhoeae pilus mapped with antibodies. Infect Immun. 1996 Feb;64(2):644-52.
Bourne Y, Arvai AS, Bernstein SL, Watson MH, Reed SI, Endicott JE, Noble ME, Johnson LN, Tainer JA. Crystal structure of the cell cycle-regulatory protein suc1 reveals a beta-hinge conformational switch. Proc Natl Acad Sci U S A. 1995 Oct 24;92(22):10232-6.
McTigue MA, Bernstein SL, Williams DR, Tainer JA. Purification and crystallization of a schistosomal glutathione S-transferase. Proteins. 1995 May;22(1):55-7.
Parge HE, Bernstein SL, Deal CD, McRee DE, Christensen D, Capozza MA, Kays BW, Fieser TM, Draper D, So M, Getzoff ED, Tainer JA. Biochemical purification and crystallization of the fiber-forming protein pilin from Neisseria gonorrhoeae. JBC. 1990 Feb 4;265(4)2278-2285.
Parge HE, McRee DE, Capozza MA, Bernstein SL, Getzoff ED, Tainer JA.
Three dimensional structure of bacterial pili. Antonie Van Leeuwenhoek. 1987;53(6):447-53.